{"id":8081,"date":"2023-05-17T14:15:17","date_gmt":"2023-05-17T12:15:17","guid":{"rendered":"https:\/\/www.grandazootecnici.it\/transizione-4-0-protocollo-di-lavoro-innovativo-per-migliorare-e-mantenere-la-salute-e-il-benessere-delle-vacche-da-latte-nel-periodo-di-periparto\/"},"modified":"2023-09-11T15:05:42","modified_gmt":"2023-09-11T13:05:42","slug":"transizione-4-0-innovative-working-protocol-to-improve-and-maintain-health-and-welfare-cow-in-the-peripartum-period","status":"publish","type":"page","link":"https:\/\/www.grandazootecnici.it\/en\/transizione-4-0-innovative-working-protocol-to-improve-and-maintain-health-and-welfare-cow-in-the-peripartum-period\/","title":{"rendered":"Transizione 4.0: innovative working protocol to improve and maintain health and welfare cows in the peripartum period"},"content":{"rendered":"

[et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.7.7″ _module_preset=”default” background_image=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/Transizione-4.0_protocollo-per-vacche-da-latte.jpg” custom_padding=”18vh||18vh||true|false” custom_padding_tablet=”” custom_padding_phone=”15vh||15vh||true|false” bottom_divider_height=”40px”][et_pb_row use_custom_gutter=”on” gutter_width=”2″ make_equal=”on” _builder_version=”4.6.6″ _module_preset=”default” width=”90%” width_tablet=”90%” width_phone=”90%” width_last_edited=”on|tablet” max_width_tablet=”90%” max_width_phone=”90%” max_width_last_edited=”on|desktop” custom_padding=”0px||100px||false|false” animation_style=”slide” animation_duration=”1500ms”][et_pb_column type=”4_4″ _builder_version=”4.6.6″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” header_font=”|700||on|||||” header_text_align=”center” header_text_color=”#ffffff” header_font_size=”60px” header_line_height=”1.1em” max_width=”900px” module_alignment=”center” header_font_size_tablet=”40px” header_font_size_phone=”30px” header_font_size_last_edited=”on|phone” header_line_height_tablet=”1.3em” header_line_height_phone=”1.3em” header_line_height_last_edited=”on|phone”]<\/p>\n

TRANSIZIONE 4.0<\/h1>\n

[\/et_pb_text][et_pb_divider divider_weight=”2px” _builder_version=”4.7.7″ _module_preset=”default” width=”150px” module_alignment=”center” custom_margin=”||0px||false|false” custom_margin_tablet=”” custom_margin_phone=”” custom_margin_last_edited=”on|desktop”][\/et_pb_divider][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” text_font=”|300|||||||” text_text_color=”#ffffff” text_font_size=”22px” text_line_height=”1.6em” text_orientation=”center” custom_margin=”25px||||false|false” custom_margin_tablet=”-10px||||false|false” custom_margin_phone=”-10px||20px||false|false” custom_margin_last_edited=”on|phone”]<\/p>\n

Innovative working protocol to improve and maintain the health and welfare cows <\/span><\/strong><\/p>\n

during the peripartum period<\/span><\/strong><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/Tranzizione-4.0_protocpllo-innovativo-per-le-vacche-in-periparto.png” alt=”Tranzizione 4.0_protocpllo innovativo per le vacche in periparto” title_text=”Tranzizione 4.0_protocpllo innovativo per le vacche in periparto” _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” custom_padding=”2px||25px|||”][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false” custom_padding=”|10px||10px|false|false”]<\/p>\n

TRANSIZIONE 4.0: INNOVATIVE WORKING PROTOCOL TO IMPROVE AND MAINTAIN HEALTH AND WELFARE COWS IN THE PERIPARTUM PERIOD (TRANSITION PERIOD)<\/span><\/h1>\n

Transition 4.0<\/strong>\u00a0is a\u00a0work protocol\u00a0<\/strong>that was created with\u00a0the aim\u00a0<\/strong>of bringing\u00a0innovative elements\u00a0<\/strong>in the analysis\u00a0<\/strong>and\u00a0in the solutions\u00a0<\/strong>applicable during the\u00a0transition period.<\/strong><\/p>\n

The “pillars”<\/strong> of dairy cows’ health in peripartum (transition period) have been consolidated for several years: Granda Team TRANSIZIONE 4.0<\/strong> program has the mission<\/strong>\u00a0to dedicate all technical\/metabolic\/nutritional efforts<\/strong> to discover and improve what which in part still remains unknown today, namely:<\/p>\n

    \n
  • the occurrence of milk hypoproduction at week 4 for a considerable percentage of cows<\/strong><\/strong><\/li>\n
  • high incidence of \u201corphan diseases\u201d in the immediate postpartum phase<\/strong><\/li>\n<\/ul>\n
    Transizione 4.0\u00ae\u00a0<\/strong>is an\u00a0exclusive project,\u00a0<\/strong>designed by\u00a0Granda Team <\/strong>and\u00a0aimed at\u00a0dairy farms.<\/strong><\/div>\n
    It’s a\u00a0support service<\/strong> that comes from the Granda Team customer service’s multi-year experience acquired directly in the field<\/strong> combining:<\/div>\n
    <\/div>\n
    <\/div>\n
    <\/div>\n
    <\/div>\n
    <\/div>\n
    <\/div>\n
      \n
    • specific and high-level technical skills,<\/strong><\/li>\n
    • innovative and scientifically tested nutritional products,<\/strong><\/li>\n
    • advanced and latest generation diagnostic tools (NUTRIL.HUB),<\/strong><\/li>\n<\/ul>\n
      <\/span><\/div>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ _builder_version=”4.7.7″ _module_preset=”default” border_width_all=”5px” border_color_all=”#f0b800″][et_pb_column type=”1_4″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/Nutril-Hub.png” alt=”Nutril-Hub pacchetto di strumenti chimico-clinico-nutrizionali” title_text=”Nutril-Hub” _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”||7px|||”][\/et_pb_text][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” width=”99.8%” custom_margin=”|-276px||||” custom_padding=”|7px||||”]<\/p>\n

      NUTRIL.HUB is the operational tool (clinical\/diagnostic laboratory)\u00a0that\u00a0GRANDA TEAM\u00a0has created\u00a0to find, convey and analyze technical data and metabolic analyzes in order to fully evaluate the incidence of peripartum (Transition period) pathologies and\u00a0the negative effects induced by them during lactation.<\/strong><\/p>\n

      [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”23px|auto|||false|false” border_radii=”on|10px|10px|10px|10px” border_width_all=”4px” border_color_all=”#f0b800″][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false”]<\/p>\n

      Objective:<\/b><\/h1>\n

      <\/b><\/p>\n

      Formulation of increasingly performing and technically up-to-date nutritional solutions<\/span><\/h2>\n

      <\/strong><\/b><\/span><\/p>\n

      <\/strong><\/b><\/span><\/p>\n

      <\/strong><\/b><\/span><\/p>\n

      Total support to the farmer in terms of service to improve and maintain the cows health and welfare in the peripartum period and the results in lactation<\/span><\/h2>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.7.7″ _module_preset=”default” custom_padding=”||73px|||”][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_video src=”https:\/\/www.youtube.com\/watch?v=hDACP9JMWZk” _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_video][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_video src=”https:\/\/www.youtube.com\/watch?v=rOP1_7t1cYw” _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_video][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” background_color=”#f0b800″ min_height=”96px” custom_padding=”14px||0px|||” border_radii=”on|10px|10px|10px|10px”][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” background_color=”rgba(0,0,0,0)” min_height=”66px” custom_margin=”10px|10px|10px|10px|false|false” custom_padding=”|10px||10px|false|false” border_radii=”on|4px|4px|4px|4px” border_color_all=”#e02b20″]<\/p>\n

      The high-performance and technically up-to-date nutritional solutions’ formulation is achieved through an in-depth and detailed RESEARCH AND DEVELOPMENT program focused on the following macro-subjects:<\/strong><\/span><\/h2>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”-15px|auto||auto||” custom_padding=”||0px|||”][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” border_width_all=”5px” border_color_all=”#f0b800″ border_width_bottom=”0px”][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false” custom_padding=”|10px||10px|false|false”]<\/p>\n

      1.\u00a0NMA (Neb Management Approach):\u00a0THE GRANDA TEAM’S ANSWER TO THE KETOSIS PROBLEM<\/strong><\/span><\/h2>\n

      “The genetic selection of the production character\u00a0will impose\u00a0an almost constant and persistent amount of lipomobilisation in the peripartum phase; therefore it’s not possible\u00a0to consider lipomobilisation a\u00a0real pathology but a metabolic necessity that we have induced and that we will have to get used to managing.”<\/em><\/p>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,3_5,1_5″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_video src=”https:\/\/www.youtube.com\/watch?v=1m_HO4BJfuI” _builder_version=”4.7.7″ _module_preset=”default” module_alignment=”center”][\/et_pb_video][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false” custom_padding=”|10px||10px|false|false”]<\/p>\n

      WHAT IS THE CORRECT APPROACH TO THE LIPOMOBILIZATION MANAGEMENT IN THE TRANSITION PHASE?<\/span><\/h3>\n

      <\/span><\/p>\n

      An innovative and all-inclusive diagnostic and nutritional approach<\/strong> that aims to help the herd<\/strong>, during peipartum phase, to manage the flow and subsequent\u00a0mobilized fats metabolization, by immediately knowing the\u00a0mobilized lipids real entity and their metabolic destiny:<\/strong> in fact, it must not be forgotten that NEFA<\/strong> and KETONS,<\/strong> even if they are not correlated in the diagnostic terms, both have the same target organ (the liver cell) <\/strong>and in a\u00a0synergistic way.\u00a0 Therefore, lipomobilisation and the subsequent fats oxidation in the liver it must be stimulated and increased,<\/strong> without neglecting or underestimating the importance of each cofactor present in this metabolic pathway.<\/p>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/Gestione-della-chetosi-nella-vacca-da-latte.jpg” alt=”Gestione della chetosi nella vacca da latte” title_text=”Gestione della chetosi nella vacca da latte” _builder_version=”4.7.7″ _module_preset=”default” custom_padding=”|||10px|false|false”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/Epatox-Transition-vacca-da-latte.jpg” alt=”Epatox Transition vacca da latte” title_text=”Epatox Transition vacca da latte” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px|||false|false” custom_padding=”|10px|||false|false”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false” custom_padding=”|10px||10px|false|false”]<\/p>\n

      GRANDA TEAM’S RESPONSE WITH TRANSIZIONE 4.0 PROGRAM<\/strong><\/span><\/h3>\n

      <\/strong><\/span><\/p>\n

      An innovative approach<\/strong> to the herd during transition period<\/strong> with specific solution use, called “Epat-ox transition”<\/strong> (Solution developed and produced by Granda Team). This specific solution, applied to dairy cows affected by NEGATIVE ENERGY BALANCE<\/strong> and\u00a0with high blood NEFA and BHBA values<\/strong>, allows to face up to the peripartum period while keeping the herd healthy and achieving\u00a0excellent production performance as well as a very low metabolic diseases incidence.<\/strong><\/span><\/p>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,3_5,1_5″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_color_bottom=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/03\/Epat-ox-transition_soluzione-nutrizionale-per-il-gruppo-preparto-che-gestisce-e-previene-la-chetosi-nelle-vacche-da-latte.png” alt=”Epat-ox transition_soluzione nutrizionale per il gruppo preparto che gestisce e previene la chetosi nelle vacche da latte” title_text=”Epat-ox transition_soluzione nutrizionale per il gruppo preparto che gestisce e previene la chetosi nelle vacche da latte” url=”https:\/\/www.grandazootecnici.it\/en\/epatox-transition-nutritional-solution-for-steaming-up-period-that-prevents-and-manages-ketosis-in-dairy-cows\/” align=”center” _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_image][et_pb_button button_url=”https:\/\/www.grandazootecnici.it\/en\/epatox-transition-nutritional-solution-for-steaming-up-period-that-prevents-and-manages-ketosis-in-dairy-cows\/” button_text=”Click and learn more about the solution” button_alignment=”center” _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,3_5,1_5″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_bottom=”5px” border_color_bottom=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_video src=”https:\/\/www.youtube.com\/watch?v=D9d3WcTeV-s” _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_video][et_pb_text _builder_version=”4.7.7″ _module_preset=”default”]<\/p>\n

      COMPLETE EPATOX TRANSITION SOLUTION WEBINAR<\/span><\/h2>\n

      [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default”][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” custom_padding=”||8px|||” border_width_top=”5px” border_color_top=”#f0b800″ border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false” custom_padding=”|10px||10px|false|false”]<\/p>\n

      2.\u00a0<\/span>CONTROLLING HYPOCALCEMIA IS NO LONGER PROBLEMATIC…<\/span><\/h2>\n

      <\/span><\/p>\n

      <\/span><\/p>\n

      SINGLE DRYING GROUP (-60 DAYS BEFORE CALVING)<\/span><\/h3>\n

      <\/span><\/p>\n

      <\/span><\/p>\n

      “NO Vitamin D3 ….. NO Ca2+ (ionized blood calcium)!!!”<\/p>\n

      “How much calcidiol is present in dairy cow in the prepartum phase?”<\/p>\n

      “Is it possible to increase the calcidiol level with vitamin D3 normally commercial sources?<\/p>\n

      <\/span><\/h3>\n

      <\/strong><\/span><\/h3>\n

      GRANDA TEAM’S RESPONSE WITH TRANSIZIONE 4.0 PROGRAM<\/strong><\/span><\/h3>\n

      <\/strong><\/span><\/p>\n

      The\u00a0DRY-CARE\u00a0<\/strong>nutritional solution proposed by\u00a0GRANDA TEAM\u00a0<\/strong>is\u00a0a new approach to the\u00a0hypocalcemia management, specially formulated for all farms <\/strong>where there is a\u00a0single DRY group\u00a0(- 60 days from calving). Effective, simple and highly performing solution.<\/strong><\/span><\/p>\n

      The hypocalcemia prevention<\/strong>, obtained with DRY CARE solution use<\/strong>, is based\u00a0on the\u00a0vitamin D3 correct reintegration\/storage.<\/strong>\u00a0This innovative solution<\/strong> also has\u00a0a stimulating effect on the dairy cow immune function dring dry period<\/strong> and positive repercussions on uterus and breast health at the calving time.<\/strong><\/span><\/p>\n

      The reintegration<\/strong> of the\u00a0HYPOAVITAMINOSIS D3 real existence in dairy cow during the dry period<\/strong> takes the form of a new and innovative technology developed and formulated by Granda Team and included in the DRY CARE solution<\/strong>, trade name<\/p>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,3_5,1_5″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/03\/Calcium-Up_soluzione-nutrizionale-tecnologica-per-aumentare-la-produzione-di-calcio-nel-metabolismo-della-vacca-da-latte-e-prevenire-ipocalcemia-clinica-e-subclinica-1.png” alt=”Calcium Up: soluzione nutrizionale tecnologica per aumentare la produzione di calcio nel metabolismo della vacca da latte e prevenire ipocalcemia clinica e subclinica” title_text=”Calcium Up_soluzione nutrizionale tecnologica per aumentare la produzione di calcio nel metabolismo della vacca da latte e prevenire ipocalcemia clinica e subclinica” _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ url=”https:\/\/www.grandazootecnici.it\/en\/dry-care-nutritional-solution-usefull-for-single-dry-group-that-prevents-clinical-and-subclinical-hypocalcemia-in-dairy-cows\/” sticky_enabled=”0″][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”-29px|auto||auto||” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false” custom_padding=”|10px||10px|false|false”]<\/p>\n

      with the aim of restoring the blood content of Vitamin D3 and its storage in the adipose tissue of the cow using technologies aimed at both ruminal protection and intestinal bioavailability.<\/strong><\/p>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,3_5,1_5″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/03\/DRY-CARE_soluzione-nutrizionale-per-gruppo-unico-di-asciutta-per-prevenire-ipocalcemia-clinica-e-subclinica-nella-vacca-da-latte-1.png” alt=”DRY-CARE_soluzione-nutrizionale-per-gruppo-unico-di-asciutta-per-prevenire-ipocalcemia-clinica-e-subclinica-nella-vacca-da-latte” title_text=”DRY CARE_soluzione nutrizionale per gruppo unico di asciutta per prevenire ipocalcemia clinica e subclinica nella vacca da latte” url=”https:\/\/www.grandazootecnici.it\/en\/dry-care-nutritional-solution-usefull-for-single-dry-group-that-prevents-clinical-and-subclinical-hypocalcemia-in-dairy-cows\/” _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_image][et_pb_button button_url=”https:\/\/www.grandazootecnici.it\/en\/dry-care-nutritional-solution-usefull-for-single-dry-group-that-prevents-clinical-and-subclinical-hypocalcemia-in-dairy-cows\/” button_text=”Click and learn more about the solution” button_alignment=”center” _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/Calcium-up-Granda-Team.jpg” alt=”Calcium up Granda Team” title_text=”Calcium up Granda Team” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|||10px|false|false” custom_padding=”|||10px|false|false”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/Dry-Care-Granda-Team.jpg” alt=”Dry Care Granda Team” title_text=”Dry Care Granda Team” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px|||false|false” custom_padding=”|10px|||false|false”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false” custom_padding=”|10px||10px|false|false” border_color_right=”#f0b800″]<\/p>\n

      STEAMING UP \/ CLOSE UP GROUP (-20 DAYS BEFORE CALVING)<\/span><\/h3>\n

      “…While recognizing\u00a0the importance of reducing potassium intake via nutrition\u00a0(Goff et al. 2004), it is nevertheless necessary to have a solution to adopt whenever the excess potassium intake is NOT manageable through choices based on forage…”<\/em><\/p>\n

      Keeping low the potassium intake in the steaming up\/close\u00a0up phase (-20 days before calving) is the goal of all nutritionists who approach the nutritional management of the TRANSITION phase.<\/strong> However, it is clear that the most suitable fodder choice and management for achieving this objective, poses serious problems for all those who manage dairy cow farms.<\/p>\n

      Al fine di calcolare correttamente il DCAD in una razione \u00e8 necessario conoscere la quantit\u00e0 totale di K+ ingerito dalle bovine,<\/strong> purtroppo per\u00f2, non \u00e8 possibile calcolarla direttamente mediante software appositamente formulati, in quanto la variabilit\u00e0 del minerale in oggetto \u00e8 estremamente ampia anche in foraggi ritenuti poveri in K+ (es. silomais o paglia)<\/strong> che sono spesso introdotti nella razione al fine di ridurre l\u2019apporto globale somministrato.<\/p>\n

       <\/p>\n

      GRANDA TEAM’S RESPONSE WITH TRANSIZIONE 4.0 PROGRAM<\/strong><\/span><\/h3>\n

      <\/strong><\/span><\/p>\n

      <\/strong><\/span><\/p>\n

      SEQUESTRATION OF EXCESS POTASSIUM<\/span><\/h4>\n

      Potassium K+ (as well as calcium) can be sequestered through a supply of aluminosilicates administered in the correct quantity.<\/strong><\/p>\n

      Therefore, it is necessary to have available a biological substrate indicator of the total potassium ingested and to know precisely the K+ amount to be sequestered; the blood determination of the same is not useful for this purpose, as the urinary excretion allows the\u00a0large quantities of mineral elimination in order to maintain a very restricted homeostasis.<\/p>\n

      The\u00a0GRANDA TEAM’S<\/strong>\u00a0CATION REM<\/strong>\u00a0solution has the ability to make a portion of potassium NON-absorbable.<\/strong><\/p>\n

      In fact, direct experimentation in the field has established that CATION REM, inserted in CLOSE UP\/STEAMING UP rations, 15 days before calving, allows a potassium absorption equal to 50% of the total intake present in the ration.<\/b><\/p>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,3_5,1_5″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/03\/CATION-REM-Soluzione-nutrizionale-per-gruppo-pre-parto-che-previene-ipocalcemia-clinica-e-subclinica-e-gestisce-variabilta-minerale-dei-foraggi-soprattuto-potassio.jpg” alt=”CATION REM Soluzione nutrizionale per gruppo pre parto che previene ipocalcemia clinica e subclinica e gestisce variabilt\u00e0 minerale dei foraggi soprattuto potassio” title_text=”CATION REM Soluzione nutrizionale per gruppo pre parto che previene ipocalcemia clinica e subclinica e gestisce variabilt\u00e0 minerale dei foraggi soprattuto potassio” url=”https:\/\/www.grandazootecnici.it\/en\/cation-rem-nutritional-solution-for-steaming-up-close-up-phase-that-prevents-clinical-and-subclinical-hypocalcemia-in-dairy-cow-and-manages-forage-mineral-variability-in-feed-ration\/” align=”center” _builder_version=”4.7.7″ _module_preset=”default” module_alignment=”center” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_image][et_pb_button button_url=”https:\/\/www.grandazootecnici.it\/en\/cation-rem-nutritional-solution-for-steaming-up-close-up-phase-that-prevents-clinical-and-subclinical-hypocalcemia-in-dairy-cow-and-manages-forage-mineral-variability-in-feed-ration\/” button_text=”Click and learn more about the solution” button_alignment=”center” _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,3_5,1_5″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_video src=”https:\/\/www.youtube.com\/watch?v=VVyLF4uDAq4&t=2s” _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_video][et_pb_text _builder_version=”4.7.7″ _module_preset=”default”]<\/p>\n

      COMPLETE CATION REM SOLUTION WEBINAR<\/span><\/h2>\n

      [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/Prevenzione-ipocalcemia-vacca-da-latte.jpg” alt=”Prevenzione ipocalcemia vacca da latte” title_text=”Prevenzione ipocalcemia vacca da latte” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|||10px|false|false” custom_padding=”|||10px|false|false”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/Cation-Rem-ipocalcemia-vacca-da-latte.jpg” alt=”Cation Rem ipocalcemia vacca da latte” title_text=”Cation Rem ipocalcemia vacca da latte” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px|||false|false” custom_padding=”|10px|||false|false”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” custom_padding=”||0px|||” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false” custom_padding=”|10px||1px|false|false”]<\/p>\n

      ANION STRATEGY<\/span><\/h4>\n

      Use\u00a0a specific solution<\/strong> for the close-up\/steaming up group<\/strong> (-20 days before calving), specifically developed and formulated by Granda Team<\/strong> (trade name DCADD<\/strong>), which contributes to achieving the anion strategy goals in a balanced and protracted way<\/strong>, thanks to a neutral effect on the final product\u00a0palatability<\/strong> and therefore without interference on the Dry Matter\u00a0ingestion capacity.<\/strong> Approximately 80% of Magnesium and Chlorine\u00a0release<\/strong> occurs at abomasal\/intestinal level<\/strong> with effective DCAD equal to -5140 meQ\/kg tq\u00a0<\/strong>allowing to obtain a targeted and effective action.<\/strong><\/span><\/p>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,3_5,1_5″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_bottom=”5px” border_color_bottom=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/03\/DCADD-soluzione-nutrizionale-per-il-gruppo-preparto-che-contribuisce-al-raggiungimento-delle-finalita-della-strategia-anionica-in-maniera-bilanciata-e-protratta-nel-tempo.jpg” alt=”DCADD soluzione nutrizionale per il gruppo preparto che contribuisce al raggiungimento delle finalit\u00e0 della strategia anionica in maniera bilanciata e protratta nel tempo” title_text=”DCADD soluzione nutrizionale per il gruppo preparto che contribuisce al raggiungimento delle finalit\u00e0 della strategia anionica in maniera bilanciata e protratta nel tempo” url=”https:\/\/www.grandazootecnici.it\/en\/dcadd-nutritional-solution-for-steaming-up-phase-that-prevents-clinical-and-subclinical-hypocalcemia-in-dairy-cows\/” align=”center” _builder_version=”4.7.7″ _module_preset=”default” module_alignment=”center” custom_margin=”-23px|||||” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_image][et_pb_button button_url=”https:\/\/www.grandazootecnici.it\/en\/dcadd-nutritional-solution-for-steaming-up-phase-that-prevents-clinical-and-subclinical-hypocalcemia-in-dairy-cows\/” button_text=”Click and learn more about the solution” button_alignment=”center” _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default”][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” custom_padding=”||12px|||” border_width_top=”5px” border_color_top=”#f0b800″ border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false” custom_padding=”|10px||10px|false|false”]<\/p>\n

      3. RUMEN HEALTH: ..BUT THE COW IS STILL A RUMINANT?? … FOR US YES !!!..<\/span><\/h2>\n

      <\/span><\/p>\n

      “Rumen health, i<\/span>n dairy cattle represents a\u00a0truly crucial aspect and the balance of this variegated “condominium” should never be lost sight of in efficiency terms but also and above all for its intrinsic pathogenicity.”<\/span><\/em><\/p>\n

      Intrinsic pathogenicity induced when the rumen begins to become\u00a0an important toxin release (LPS) source, as well as compounds that cannot be metabolized once they enter in the bloodstream, such as D-lactates.<\/span><\/strong><\/p>\n

      LPS are endotoxins present in the Gram bacteria’s membrane, which dwell in the ruminal area even if in an absolutely lower quantity than Gram + bacteria. Their concentration increases in the subclinical rumen acidosis\u00a0(SARA) <\/span>presence conditions (Khafipour et al., 2011), inducing a corresponding LPS’s\u00a0<\/span>increase. These becomes significantly relevant when the acidosis becomes acute (Ametay et al., 2010, 2011).\u00a0 LPS translocation\u00a0<\/span>predisposes the dairy cow to an acute systemic endotoxicosis due to the severity of LPS-induced toxemia (Emmanuel et al., 2007, 2008).<\/span><\/p>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/Salute-del-rumine-vacca-da-latte.jpg” alt=”Salute del rumine vacca da latte” title_text=”Salute del rumine vacca da latte” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|||10px|false|false” custom_padding=”|||10px|false|false”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/tox-rem-Granda-Team.jpeg” alt=”Salute del rumine vacca da latte” title_text=”Cows in a farm. Dairy cows” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px|||false|false” custom_padding=”|10px|||false|false”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false” custom_padding=”|10px||10px|false|false”]<\/p>\n

      GRANDA TEAM’S RESPONSE WITH TRANSIZIONE 4.0 PROGRAM<\/strong><\/span><\/h3>\n

      <\/strong><\/span><\/p>\n

      <\/strong><\/span><\/p>\n

      Pay due attention to the rumen adaptation to the lactation ration, taking advantage from informations from the various studies carried out in this regard which show the importance of avoiding abrupt variations between the dry diet, close up\/steaming up and post partum\/lactation diet.<\/strong><\/span><\/p>\n

      It is crucial to be able to reduce the LPS negative effects as well as their passage into the circulation, <\/strong>regardless of prepartum period management type and in consideration of the inevitable variations in the rumen ecosystem that characterize this phase.\u00a0This\u00a0objective can be achieved through specific LPS inactivator use (\u201cLPS binder\u201d). Trade name: TOX REM.<\/strong><\/p>\n

      Recent\u00a0analyses highlight extremely positive results about the high-producing cows physiometabolic balance following the TOX REM use in the post partum\/lactation period as a specific and effective LPS inhibitor.<\/strong><\/p>\n

      This nutritional solution activity also appears to be independent of the circulating endotoxins level, resulting effective even in the high concentrations presence.<\/strong><\/p>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,3_5,1_5″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/03\/Tox-rem_soluzione-nutrizionale-per-il-gruppo-post-parto-e-lattazione-che-previene-infiammazione-e-acidosi-ruminale-nelle-vacche-da-latte-mantenendo-rumine-in-salute.jpg” alt=”Tox Rem: soluzione nutrizionale per il gruppo post parto e lattazione che previene infiammazione e acidosi ruminale nelle vacche da latte mantenendo rumine in salute” title_text=”Tox rem_soluzione nutrizionale per il gruppo post parto e lattazione che previene infiammazione e acidosi ruminale nelle vacche da latte mantenendo rumine in salute” url=”https:\/\/www.grandazootecnici.it\/en\/tox-rem-nutritional-solution-usefull-in-postpartum-lactation-phase-that-prevents-inflammation-and-rumen-acidosis-by-keeping-healthy-dairy-cows-rumen\/” align=”center” _builder_version=”4.7.7″ _module_preset=”default” module_alignment=”center” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_image][et_pb_button button_url=”https:\/\/www.grandazootecnici.it\/en\/tox-rem-nutritional-solution-usefull-in-postpartum-lactation-phase-that-prevents-inflammation-and-rumen-acidosis-by-keeping-healthy-dairy-cows-rumen\/” button_text=”Click and learn more about the solution” button_alignment=”center” _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,3_5,1_5″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_bottom=”5px” border_color_bottom=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_video src=”https:\/\/www.youtube.com\/watch?v=k0fJ-DKbwtg&t=1s” _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_video][et_pb_text _builder_version=”4.7.7″ _module_preset=”default”]<\/p>\n

      COMPLETE TOX REM SOLUTION WEBINAR<\/span><\/h2>\n

      [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default”][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” custom_padding=”||0px|||” border_width_top=”5px” border_color_top=”#f0b800″ border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false” custom_padding=”|10px||10px|false|false”]<\/p>\n

      4. DAIRY COWS FERTILITY: …MORE PROGESTERONE … LESS INFLAMMATION…PLEASE!!<\/span><\/h2>\n

      <\/span><\/p>\n

      <\/span><\/p>\n

      “Progesterone is essential for the normal reproductive cycle; it inhibits estrus and controls follicle growth. But some high-producing dairy cows have not enough of it in circulation.” <\/span>Penn State University.<\/strong><\/span><\/em><\/p>\n

      \u201cP4 circulating concentrations represent a balance between P4 production and P4’s metabolism; P4’s metabolism is primarily related to the\u00a0blood flow’s amount to the liver due to the enzymes abundance in bovine liver that mediate P4 metabolism.\u201d M.C.Wiltbank,\u00a0A.H.Souza, P.D. Carvalho,\u00a0A.P.Cunha,\u00a0J.O.Giordano,\u00a0P.M.Fricke,\u00a0G.M.Baez\u00a0and M.G. Diskin, 2014<\/em><\/strong><\/p>\n

      <\/em><\/strong><\/p>\n

      INFLAMMATION and FERTILITY: a difficult relationship<\/b><\/em><\/p>\n

        \n
      • Reduction in the FSH and LH hormones production (less follicular development and ovulation absence)<\/em><\/li>\n
      • Luteolytic action of prostaglandins: blood progesterone reduction and embryonic mortality<\/em><\/li>\n
      • Uterine action: glandular epithelium reduction: > embryonic resorptions<\/em><\/li>\n<\/ul>\n

        [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/ipofertilita-bovina-controflox-granda-team.jpg” alt=”ipofertilit\u00e0 bovina controflox granda team” title_text=”ipofertilit\u00e0 bovina controflox granda team” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|||10px|false|false” custom_padding=”|||10px|false|false”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/Ipofertilita-bovina_promega-plus-granda-team.jpg” alt=”Ipofertilit\u00e0 bovina_promega plus granda team” title_text=”Ipofertilit\u00e0 bovina_promega plus granda team” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px|||false|false” custom_padding=”|10px|||false|false”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px||10px|false|false” custom_padding=”|10px||10px|false|false”]<\/p>\n

        2.<\/span>GRANDA TEAM’S RESPONSE WITH TRANSIZIONE 4.0 PROGRAM<\/strong><\/span><\/h3>\n

        Restoring fertility within a dairy cows herd<\/strong> is not only the specific product’s research and use dedicated to it<\/strong>, but it effectively materialize in an application model that takes into consideration all the predisposing factors that have interfered with performance. <\/strong>GRANDA TEAM TRANSIZIONE 4.0 program<\/strong> is positioned in this way, as a systemic solution in programs and protocols support and in herd’s health and fertility support.<\/strong><\/p>\n

        The cow’s ovarian cycle study has shown that the fertile follicle’s development depends on two metabolically correlated factors:<\/em><\/strong><\/span><\/p>\n

        –\u00a0the blood progesterone concentration<\/strong><\/p>\n

        – the systemic inflammation reduction present in postpartum phase, especially in the summer (“heat stress”)<\/strong><\/p>\n

        The fertility hormone (progesterone) concentration<\/strong> and\u00a0the inflammatory stress quantification <\/strong>are, therefore, the two key factors to be analyzed\u00a0in the fight against dairy cows hypofertility, especially in “stressogenic”\u00a0factors precence <\/strong>that work in a negative sense in the new pregnancy\u00a0establishment (heat stress, mycotoxins, etc\u2026)<\/strong><\/p>\n

        The dairy cows fertility management according to the Granda Team TRANSITION 4.0 protocol takes the form of the following steps:<\/strong><\/p>\n

        1. ACCURATE HERD SCREENING DIRECTLY ON THE FARM<\/strong><\/span><\/h2>\n

        (Through the NUTRIL.HUB (made GRANDA TEAM) diagnostic\/technological support)<\/span><\/strong><\/p>\n

        <\/span><\/strong><\/p>\n

        2. BLOOD PROGESTERONE DETERMINATION<\/h2>\n

         <\/p>\n

        3. SISTEMIC INFLAMMATION DETERMINATION<\/h2>\n

         <\/p>\n

        4. ACCURACY AND PRECISION\u00a0HEATS DETECTION<\/h2>\n

        (Through the technological GRANDA TOOLS – COW MONITORING system support)<\/span><\/strong><\/p>\n

        [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default”]<\/p>\n

        TO CONTRAST THE BLOOD PROGESTERONE DEFICIENCY<\/strong><\/p>\n

        [\/et_pb_text][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/03\/Promega-plus_gestione-della-fertlita-nella-vacca-bovina-da-latte.png” alt=”Promega plus: gestione della fertlit\u00e0 nella vacca-bovina da latte” title_text=”Promega plus_gestione della fertlit\u00e0 nella vacca-bovina da latte” url=”https:\/\/www.grandazootecnici.it\/en\/promega-plus-fertility-management-in-dairy-cows\/” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|||10px|false|false” custom_padding=”|||10px|false|false” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_image][et_pb_button button_url=”https:\/\/www.grandazootecnici.it\/en\/promega-plus-fertility-management-in-dairy-cows\/” button_text=”Click and learn more about the solution” button_alignment=”center” _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”||66px|||”]<\/p>\n

        TO CONTRAST THE SYSTEMIC INFLAMMATION PRESENCE<\/strong><\/p>\n

        [\/et_pb_text][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/Controflox_infiammazione-bovina-da-latte.png” alt=”Controflox_infiammazione bovina da latte” title_text=”Controflox_infiammazione bovina da latte” url=”https:\/\/www.grandazootecnici.it\/en\/project\/controflox\/” _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|10px|70px||false|false” custom_padding=”|10px|||false|false” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_image][et_pb_button button_url=”https:\/\/www.grandazootecnici.it\/en\/project\/controflox\/” button_text=”Click and learn more about the solution” button_alignment=”center” _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_5,3_5,1_5″ _builder_version=”4.7.7″ _module_preset=”default” border_width_right=”5px” border_color_right=”#f0b800″ border_width_bottom=”5px” border_color_bottom=”#f0b800″ border_width_left=”5px” border_color_left=”#f0b800″][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default”]<\/p>\n

        FOR PRECISE AND ACCURATE HEAT DETECTION<\/strong><\/p>\n

        [\/et_pb_text][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/04\/GRANDA-TOOLS_precision-feeding.png” alt=”GRANDA TOOLS_precision feeding” title_text=”GRANDA TOOLS_precision feeding” url=”https:\/\/www.grandazootecnici.it\/en\/granda-tool-cow-monitoring-herd-monitoring-and-management-system-heat-feeding-rumination-inactivity-signals\/” align=”center” _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_image][et_pb_button button_url=”https:\/\/www.grandazootecnici.it\/en\/granda-tool-cow-monitoring-herd-monitoring-and-management-system-heat-feeding-rumination-inactivity-signals\/” button_text=”Click and learn more about the solution” button_alignment=”center” _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_5″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Sezione” _builder_version=”4.7.7″ _module_preset=”default” background_color=”#f1f1f1″ animation_style=”fade” saved_tabs=”all”][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” width=”97%” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false”][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default”]<\/p>\n

        KEEP\u00a0IN TOUCH<\/span><\/h2>\n

        ask GRANDA TEAM expert<\/p>\n

        [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ _builder_version=”4.7.7″ _module_preset=”default” width=”97%”][et_pb_column type=”1_4″ _builder_version=”4.7.7″ _module_preset=”default” animation_style=”slide” animation_direction=”bottom” animation_delay=”500ms”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default”]

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        <\/p>

          <\/ul><\/div>\n
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