{"id":8148,"date":"2023-01-11T18:07:22","date_gmt":"2023-01-11T17:07:22","guid":{"rendered":"https:\/\/www.grandazootecnici.it\/epatox-transition-soluzione-nutrizionale-per-il-gruppo-preparto-che-previene-e-gestisce-la-chetosi-nelle-vacche-da-latte\/"},"modified":"2026-06-22T18:01:22","modified_gmt":"2026-06-22T16:01:22","slug":"nutritional-solution-steaming-up-prevents-manages-ketosis-dairy-cows","status":"publish","type":"page","link":"https:\/\/www.grandazootecnici.it\/en\/nutritional-solution-steaming-up-prevents-manages-ketosis-dairy-cows\/","title":{"rendered":"Epatox Transition: nutritional solution for steaming up period that prevents and manages ketosis in dairy cows"},"content":{"rendered":"

[et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” _builder_version=”4.7.7″ _module_preset=”default” background_image=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/03\/Soluzione-nutrizionale-per-il-gruppo-preparto-che-gestisce-e-previene-la-chetosi-nelle-vacche-da-latte.jpg” custom_padding=”18vh||18vh||true|false” custom_padding_tablet=”” custom_padding_phone=”15vh||15vh||true|false” bottom_divider_height=”40px”][et_pb_row use_custom_gutter=”on” gutter_width=”2″ make_equal=”on” _builder_version=”4.6.6″ _module_preset=”default” width=”90%” width_tablet=”90%” width_phone=”90%” width_last_edited=”on|tablet” max_width_tablet=”90%” max_width_phone=”90%” max_width_last_edited=”on|desktop” custom_padding=”0px||100px||false|false” animation_style=”slide” animation_duration=”1500ms”][et_pb_column type=”4_4″ _builder_version=”4.6.6″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” header_font=”|700||on|||||” header_text_align=”center” header_text_color=”#ffffff” header_font_size=”60px” header_line_height=”1.1em” max_width=”900px” module_alignment=”center” header_font_size_tablet=”40px” header_font_size_phone=”30px” header_font_size_last_edited=”on|phone” header_line_height_tablet=”1.3em” header_line_height_phone=”1.3em” header_line_height_last_edited=”on|phone”]<\/p>\n

epatox transition<\/span><\/h1>\n

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Nutritional solution for ketosis management in dairy cows<\/strong><\/span><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.7.7″ _module_preset=”default” custom_padding=”4px|||||”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_image src=”https:\/\/www.grandazootecnici.it\/wp-content\/uploads\/2023\/03\/Epat-ox-transition_soluzione-nutrizionale-per-il-gruppo-preparto-che-gestisce-e-previene-la-chetosi-nelle-vacche-da-latte.png” alt=”ketosis in dairy cows \/ in cattle” title_text=”ketosis in dairy cows \/ in cattle” _builder_version=”4.7.7″ _module_preset=”default” width=”90%” max_width=”90%” module_alignment=”center”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.7.7″ _module_preset=”default”][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.7.7″ _module_preset=”default” custom_margin=”|auto|-2px|auto||” custom_padding=”2px||25px|||”][et_pb_column type=”4_4″ _builder_version=”4.7.7″ _module_preset=”default”][et_pb_text _builder_version=”4.7.7″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n

EPATOX TRANSITION: NUTRITIONAL SOLUTION <\/span><\/h1>\n

FOR KETOSIS PREVENTION AND MANAGEMENT IN DAIRY COWS<\/span><\/h1>\n

EPATOX TRANSITION is Granda Team\u2019s nutritional solution designed to support transition dairy cows by optimizing the NEFA’s energy use and the\u00a0negative energy balance (NEB) management.<\/strong><\/p>\n

The transition period is one of the most delicate phases in the dairy cow’s productive life. Genetic selection and the increase in productive performance have led the modern cow to produce more energy than feed intake can cover during the early stages of lactation.<\/p>\n

This phenomenon is known as <\/span>NEB \u2013 Negative Energy Balance<\/span><\/strong>. In this condition, the cow mobilizes lipid and muscle reserves to support production, metabolism, and postpartum adaptation.<\/span><\/p>\n

We begin to consider lipid metabolism as a chain in which there may be “weak” links to be supported with correct integration in order not to induce hepatic oxidation phenomena with its often harmful consequences;<\/strong> in this perspective, the correlation between NEFA and integration becomes a managerial key and metabolic factor which will manifest itself with an increase in dairy cows health during transition phase.<\/strong><\/p>\n

The goal is not to look for a low incidence of NEFA or BHBA in immediate postpartum period, but to help to make the liver able to metabolize these lipids without inducing hepatic suffering and related pathologies.<\/strong><\/p>\n

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GRANDA TEAM’S RESPONSE WITH TRANSIZIONE 4.0 PROGRAM<\/strong><\/span><\/h3>\n

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It is possible to face peripartum period<\/strong> while managing to achieve excellent production performances as well as a very low incidence of metabolic pathologies <\/strong>t<\/span><\/span>hrough a new herd approach\u00a0during transition period (NMA\u00ae NEB Management approach by Granda Team Transizione 4.0)<\/strong>\u00a0and with a specific solution use<\/strong> (Epatox Transition solution designed and produced by Granda Team)<\/strong>, applied to dairy cows affected by NEB<\/strong> and with high blood NEFA and BHBA values.<\/strong><\/span><\/p>\n

Lipid mobilization is<\/strong> an extremely punctual datum, variable in very short times, but above all not correlated between prepartum analyzes and postpartum analyses<\/strong>; finding low levels of NEFA in prepartum (< 0.4 mmol\/L) does not guarantee the presence of low levels of NEFA even in the postpartum phase.<\/strong> It is evident that the datum to be absolutely taken into consideration consists both of sampling time (pre and post calving days) and of\u00a0 marker considered type.<\/p>\n

According to Granda Team TRANSITION 4.0 protocol<\/strong>, the true lipomobilisation marker is represented by NEFAs<\/strong> determined in postpartum phase<\/strong> and therefore herd screening should be set up and dedicated to the determination of these<\/strong> rather than spending time and money on the others indirect and not directly related markers\u00a0determination.<\/p>\n

Use a specific technological solution (EPATOX TRANSITION),<\/strong> administered to the entire herd during transition phase,<\/strong> which contains all the necessary precursors for NEFA metabolic use for energy purposes.<\/strong><\/p>\n

This integrative solution use allows the treated cows to perform optimally both in terms of postpartum pathologies incidence<\/strong> and in terms of subsequent lactation production while showing high blood NEFA and BHBA values.<\/strong><\/p>\n

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KEY POINTS TO FOLLOW IN KETOSIS\u00a0<\/strong><\/span>MANAGING <\/strong><\/span>WITH GRANDA TEAM’S TRANSITION 4.0 PROTOCOL:<\/strong><\/span><\/h3>\n

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Evaluating NEB condition using NEFA quantification in the immediate post partum period, taking a 0.8 mmol\/L value as a scientifically validated cut-off point<\/b><\/p>\n

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Quantify\u00a0cows’ percentage showing values greater than 0.8 mmol\/L<\/strong><\/p>\n

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In case of\u00a0 cows’ incidence with NEFA > 0.8 mmol\/L value more than 20%, consider a specific additive (EPATOX TRANSITION) aimed at optimizing the mobilized fats use for energy purposes<\/strong><\/p>\n

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Not consider ketosis quantification as to be the sole representative NEB parameter<\/strong><\/p>\n

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Not consider BCS or NEFA concentration in prepartum period to be correlated with postpartum NEB values<\/strong><\/p>\n

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KEEP\u00a0IN TOUCH<\/span><\/h2>\n

ask GRANDA TEAM expert<\/p>\n

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