MYCOX REM

Nutritional solution to fight against mycotoxin contamination

Mycox Rem_soluzione nutrizionale per prevenire e combattere la contaminazione da micotossine

MYCOX REM – NUTRITIONAL SOLUTION TO FIGHT AGAINST MYCOTOXIN CONTAMINATION

In recent years, we have understood that it’s very important to carry out a constant and accurate all components that feed our animals monitoring action because they can bring undesirable substances.

Due to the spring-summer meteorological trend, we are facing a mycotoxin emergency which mainly concerns the toxins generated by Fusarium widespread attacks. Although FUSARIUM is a ubiquitous mushroom, it multiplies quickly in the high humidity and cool temperatures presence.

MYCOTOXIN EMERGENCY MUST WORRY FARMERS

Mycotoxicoses represent a very serious health and economic problem in cattle beef and dairy farming.
Mycotoxins alter ruminal function, causing malabsorption in the intestine, which results in a lower essential nutrients availability for immune activity and to support adequate production performance.

The mycotoxins’ presence also promotes the reactive oxygen species’ production both locally and systemically, with consequent antioxidant reserves’ cytotoxic effects and depletion.

The symptoms manifested by the animal, or much more frequently by the herd, are also decidedly complex as they are very different in severity’s terms and very varied as regards the clinical manifestations. Different mycotoxins are often produced simultaneously by several fungal strains, giving synergies’ origin that are not yet fully defined and codified.

The negative effects caused by mycotoxicosis on dairy and beef farm are as follows:

REDUCED MILK PRODUCTION 

 IMPAIRED RUMEN FUNCTION 

REDUCED POOR GROWTH AND BODY WEIGHT 

REDUCED FERTILITY, ABORTIONS

IMMUNE SUPPRESSION

 COMPROMISED BREAST HEALTH

 INCREASED SOMATIC CELL COUNT 

GRANDA TEAM’s MYCOX REM program:

BIND – NEUTRALIZE – TRANSFORM

mycotoxin molecules

In particular:

Mineral clay particles – BIND “POLAR” MYCOTOXINS

Yeast wall’s components – BIND TOXINS AND PATHOGENIC BACTERIA

Microbial nutrient’s pack – HELPS TISSUES AND THE BENEFICIAL MICROFLORA PROLIFERATION

Biologically active components – THEY ACT ON MYCOTOXINS, MAKING THEM INACTIVE AND UNAVAILABLE

goals:

If there is mycotoxins’ presence in the naimal’s feed, treatment with MYCOX REM can bring about:

Increased feed intake

Increased milk production

Better growing times

Increased fertility

Lower litters and herd mortality

Better health state

micotossine_medica
micotossine_trincea

CASE 1: DAIRY COWS

-610 cows in lactation
– Average milk production: 28.6 litres
– Divided into 2 groups of 75 cows for each group, the fresh multiparous (equivalent in production, performance and lactation days terms):

1. CONTROL group treated with a generic mycotoxin inactivator (Clinoptilolite) at a quantity of 150 g/cow/day;

2. TEST group treated with a technological mycotoxin inactivator (MYCOX REM by Granda Team) at a quantity of 15 g/cow/day.

COMPANY SCENARIO

 

Ascertained mycotoxins’ precence in the unifeed on the opening’s occasion of the new corn silage trench:

Micotossicosi_unifeed

Problems encountered on animals:

– Sharp decline in reproductive and productive performance

– Strong increase in heat returns

– Strong increase in the calving-conception interval

– Percentage reduction of pregnant cows

– Increase in abortions

PRODUCTION PERFORMANCE 

Micotossine_performance produttive

The GREY COLUMN indicates the month of the mycotoxin problem’s onset, the RED boxes indicate the results obtained by the CONTROL GROUP, the GREEN boxes indicate the results obtained by the TEST GROUP WITH MICOX REM.

The TEST group’s animals show an improvement in the average milk production up to the productions’ achievement prior to the problem’s beginning after one month of MYCOX REM’s administration, the somatic cells return to normal after 3 months of administration.

HEALTH PROBLEMS

Micotossine_problemi sanitari

The GREY COLUMN indicates the month of the mycotoxin problem’s onset, the RED boxes indicate the results obtained by the CONTROL GROUP, the GREEN boxes indicate the results obtained by the TEST GROUP WITH MICOX REM.

Within 3 months from the beginning of  MYCOX REM’s administration, the health problems and the somatic cells’ count in the milk also returned to normal.

REPRODUCTIVE PERFORMANCE

Micotossine_performance riproduttive

The GREY COLUMN indicates the month of the mycotoxin problem’s onset, the RED boxes indicate the results obtained by the CONTROL GROUP, the GREEN boxes indicate the results obtained by the TEST GROUP WITH MICOX REM.

Within 3 months from the beginning of MYCOX REM’s administration, the herd’s reproductive capacity indicators were brought back to values comparable to the circumstances preceding the problem’s onset.

BLOOD PARAMETERS

The positive results obtained, in addition to being attributable to the positive effects that an effective mycotoxin inactivator (Mycox Rem) exerts on the dry matter intake and on rumen fermentations, can also be explained by an overall improvement in the physiological and immune animals’ status.
The blood parameters carried out 60 days after the intervention showed a clear improvement, with significant differences compared to the control group, in the immune, antioxidant and inflammatory states, which instead remained in conditions considered to be at risk in the control animals.

CASE 2: DAIRY COWS

-280 cows in lactation
– Average milk production: 30 litres
– Divided into 2 groups, the fresh multiparous (equivalent in production, performance and lactation days terms):

1. CONTROL group treated with a generic mycotoxin inactivator (Clinoptilolite) at a quantity of 150 g/cow/day;

2. TEST group treated with a technological mycotoxin inactivator (MYCOX REM by Granda Team) at a quantity of 15 g/cow/day.

COMPANY SCENARIO

Found mycotoxins’ precence in the dry and lactation unifeed at the new silomais trench’s opening and a banded alfalfa not excellent:

Micotossicosi_unifeed_1

Problems encountered on animals:

5 mortality’s cases in the lactation group

Strong Dry Matter’s ingestion reduction 

Average productivity reduction

Reduction of faecal consistency up to diarrhea with poorly digested faeces and traces of blood

Health status’ worsening with an increase in heat returns

PRODUCTION PERFORMANCE

Micotossine_performance produttive_1

The GREY COLUMN indicates the month of the mycotoxin problem’s onset, the RED boxes indicate the results obtained by the CONTROL GROUP, the GREEN boxes indicate the results obtained by the TEST GROUP WITH MICOX REM.

The treatment group showed a rapid recovery of the milk production’s average, reaching production performance prior to the problem’s onset in just 60 days.

REPRODUCTIVE PERFORMANCE

Micotossine_performance riproduttive_1

The GREY COLUMN indicates the month of the mycotoxin problem’s onset, the RED boxes indicate the results obtained by the CONTROL GROUP, the GREEN boxes indicate the results obtained by the TEST GROUP WITH MICOX REM.

The treatment group showed a rapid improvement in reproductive performance, reaching values similar to the period prior to the problem’s onset in just 60 days.

HEALTH PROBLEMS

Micotossine_problemi sanitari_1

The GREY COLUMN indicates the month of the mycotoxin problem’s onset, the RED boxes indicate the results obtained by the CONTROL GROUP, the GREEN boxes indicate the results obtained by the TEST GROUP WITH MICOX REM.

The treatment group showed a rapid improvement in the health situation, reaching values similar to the period prior to the problem’s onset within about 60 days.

Mycotoxicosis is a serious problem in cattle farming.

The problem’s perception varies greatly among livestock realities, not only due to different sensitivity and management attention but also, and above all, due to the symptoms that are often variable and not constant over time, especially in  prolonged exposure’s cases to low toxins’ levels.

These variability in manifestation and perception influence the time between the problem’s onset and the nutritional intervention with serious repercussions for the farm’s profitability.

Mycotoxins cause not only the herd’s health status deterioration due to their specific toxicity but also the defensive capacities’ reduction in apparently healthy animals, also increasing the incurring pathological phenomena’s risk in them.

By negatively interfering with rumen fermentations, in addition to further increasing this risk, they significantly and strikingly reduce production and reproductive performance.

In this regard, it must be remembered that mycotoxicosis can also occur only with a reduction in zootechnical performance.

The MYCOX REM’s use in the mycotoxicosis’ management represents a valid strategy able to quickly achieve the herd’s normal conditions restoration as regards:

  • health status
  • productive and reproductive performance
  • immune status
  • inflammatory state
  • antioxidant status.
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